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Cytogenetic Oncology

Cytogenetic oncology testing is available for a variety of indications including hematologic neoplasms and pediatric oncology. We perform G-Banding karyotype and Fluorescent In Situ Hybridization (FISH). Testing that is not available in-house is referred to Mayo Clinic Laboratories. Please refer to the requisition for details.

*This testing is limited to Hematology, Hematopathology and Pathology.*

Sample Requirements and Storage

Bone Marrow: Collect a minimum of 2mL bone marrow in green NaHep. Do not centrifuge or freeze specimen. Ship to the laboratory at room temperature within 24 hours.

Bone core trephine biopsy: Collect 2-3 cm bone core (if possible) into a sterile specimen jar containing sterile culture media or saline. Do not freeze. Ship to the laboratory at room temperature within 24 hours.

Peripheral Blood: (NOTE: cytogenetic oncology testing is only possible on peripheral blood if there are ≥10% circulating blasts). Collect 4mL peripheral blood in green NaHep IWK meditech CG. Do not centrifuge or freeze specimen. Ship at room temperature within 24 hours.

Lymph Node/Tumour: Collect a 1cm3 specimen (where possible) fresh tumour/lymph node tissue into a specimen jar containing sterile saline or media. Do not freeze. Send to the laboratory at 4˚C within 24 hours.

Refer to our sample storage and retention section for more background on our banking policy:
https://iwkhealth.ca/health-professionals/clinical-genomics/general-sam…